Leonard has not scored a goal since early March, posting just seven assists and 41 shots in his last 29 games. He will be replaced by Sasha Chmelevski in the lineup on Wednesday.
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Donato has picked up just two assists while averaging 10:46 TOI over his last 15 games. Alexander True will replace him in the lineup on Wednesday.
Meloche has spent most of the season in the AHL, posting eight assists in 27 games. He had one assist in six NHL games earlier in the season and will replace Christian Jaros in the lineup on Wednesday.
True was a healthy scratch on Monday but will replace John Leonard in the lineup on Wednesday. True had one assist and four shots in his previous three games.
Chmelevski has spent most of the year in the AHL but has appeared in the first two games of his NHL career earlier in the season. The 21-year-old, who will most likely suit up on the fourth line, has nine goals and 11 assists (20 points) in 27 AHL games.
Pacioretty will be scratched for a second straight game on Wednesday, meaning Mattias Janmark will remain in the top-6 and Peyton Krebs will remain in the lineup. Pacioretty's injury is not believed to be serious, so holding him out is likely more precautionary.
Johansson has missed the last two games with an upper-body injury but will be a game-time decision on Wednesday. Johansson would likely replace Nick Bjugstad or Nico Sturm and skate on a line with Victor Rask and Kevin Fiala if he plays.
Sissons missed Monday's game in Columbus but could be back in the lineup on Wednesday. Sissons will most likely replace Brad Richardson if he is able to play.
Fabbro has been out since April 6th but could be back in the lineup Wednesday in Columbus. Fabbro scored two goals and nine assists (11 points) in 38 games this season. He will likely replace Alexandre Carrier if he can play.
Tarasenko re-aggravated his lower-body injury and will not play Wednesday. This will be the third time in four games that Tarasenko is unavailable. Look for Zach Sanford to move up and play with Tyler Bozak and Jaden Schwartz.
Gurianov was questionable for Monday's game but was able to suit up. On Wednesday it looks as if the opposite will be true. Expect Joel Kiviranta to move up and skate with Tyler Seguin and Jamie Benn.
Dickinson missed Monday's game with a lower-body injury that he suffered on Saturday. Dickinson will most likely replace Rhett Gardner in the lineup and centre the fourth line if he plays on Wednesday.
Schultz missed Monday's game in New York but could be available for Wednesday's rematch. Schultz took part in the morning skate, which is typically a good sign for his availability tonight but he remains a game-time decision.